Which Topics Are Commonly Tested on the AANP and ANCC Nurse Practitioner Exams?


Both exams assess your knowledge, clinical reasoning, and ability to provide safe and effective care. However, they differ slightly in content and emphasis, so knowing what to expect is important.

1. Clinical Management: You will need to be able to diagnose and manage various conditions across the lifespan.

You can expect to see questions on:

  • Acute and Chronic Conditions: Conditions like hypertension, diabetes, asthma, COPD, and heart disease are frequently tested. You’ll need to demonstrate your understanding of pathophysiology, treatment options, and patient education.
  • Pharmacology: This includes choosing appropriate medications, understanding drug interactions, side effects, and contraindications. You’ll also be tested on adjusting medications based on patient response.
  • Health Promotion and Disease Prevention: Questions often focus on age-appropriate screenings, immunizations, and lifestyle modifications. You’ll need to know the guidelines for preventive care and how to apply them to different patient populations.
2. Diagnostic Testing and Interpretation: Understanding how to order, interpret, and act upon diagnostic tests.

Both exams will test your ability to:

  • Order Appropriate Tests: Based on patient history and symptoms, you’ll be expected to choose the most appropriate lab tests, imaging studies, or other diagnostics.
  • Interpret Results: You’ll need to accurately interpret results, recognizing what is normal, what indicates a need for further investigation, and what requires immediate intervention.
  • Formulate a Plan: Based on test results, you’ll be tested on your ability to create an effective plan of care, including follow-up and referral when necessary.
3. Patient Assessment: Both exams will assess your ability to conduct a comprehensive patient assessment.

This includes:

  • History Taking: You’ll need to know how to gather a thorough and relevant patient history, including medical, surgical, social, and family history.
  • Physical Examination: You’ll be tested on your ability to perform a complete physical exam and recognize normal versus abnormal findings.
  • Differential Diagnosis: Based on your assessment, you’ll need to develop a differential diagnosis and determine the most likely condition.
4. Professional Issues: The ANCC exam places a greater emphasis on professional issues compared to the AANP exam.

Topics you’ll see include:

  • Scope of Practice: Understanding the legal and ethical boundaries of nurse practitioner practice, including state-specific regulations.
  • Evidence-Based Practice: You’ll need to demonstrate knowledge of research methods, quality improvement, and how to apply evidence-based guidelines to clinical practice.
  • Health Policy and Leadership: Questions may focus on the role of nurse practitioners in healthcare policy, leadership, and advocacy.
5. Special Populations: Both exams will include questions on the care of special populations, including:
  • Pediatrics: Growth and development, common pediatric conditions, immunizations, and anticipatory guidance.
  • Geriatrics: Managing chronic conditions, polypharmacy, fall prevention, and age-related changes.
  • Women’s Health: Reproductive health, contraception, pregnancy, menopause, and common gynecological issues.
  • Mental Health: Assessment and management of common psychiatric conditions like depression, anxiety, and substance use disorders.
6. Clinical Guidelines and Best Practices: You’ll be expected to know and apply current clinical guidelines.
  • Screening and Preventive Guidelines: Familiarize yourself with guidelines from organizations like the USPSTF for screening and preventive care.
  • Management Guidelines: Know the latest evidence-based guidelines for managing common conditions, such as those from the American Diabetes Association or the American Heart Association.
7. Key Differences Between the AANP and ANCC Exams: while the content is similar, there are key differences to keep in mind:
  • AANP Exam: This exam is more clinically focused, with an emphasis on clinical management and direct patient care. It’s ideal for those who prefer a straightforward, clinically-oriented exam.
  • ANCC Exam: This exam includes a broader range of topics, including professional issues like healthcare policy, leadership, and research. It’s suitable for those who want a more comprehensive exam that covers both clinical and professional aspects of nurse practitioner practice.

Good luck with your studies and exam preparation! And make sure to check out the practice questions on our site that are expertly written to help you pass! You got this!